Genomes of diploblastic organisms contain homeoboxes: sequence of eveC, an even-skipped homologue from the cnidarian Acropora formosa.

@article{Miles1992GenomesOD,
  title={Genomes of diploblastic organisms contain homeoboxes: sequence of eveC, an even-skipped homologue from the cnidarian Acropora formosa.},
  author={Annabel Miles and David J. Miller},
  journal={Proceedings. Biological sciences},
  year={1992},
  volume={248 1322},
  pages={159-61}
}
We report the nucleotide sequence of eveC, a cnidarian eve-class homeobox; this is the first homeobox to be identified in any diploblastic organism, and is only the second eve-class in an invertebrate. Similarity between the predicted amino acid sequence of the eveC homeodomain and its insect and vertebrate equivalents was approximately 75-80% but, in the case of eveC, a role in segmentation can be ruled out. Our findings thus support the 'co-option' hypothesis: homeoboxes were an early feature… CONTINUE READING

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