Bayesian Modeling of Epigenetic Variation in Multiple Human Cell Types
A unified Bayesian framework for jointly annotating multiple epigenomes and detecting differential regulation among multiple tissues and cell types over regions of varying sizes is developed, which achieves superior power and accuracy over existing methods.
Estimating Statistical Measures of Pleiotropic and Epistatic Effects in the Genomic Era
Ability to use working definitions of alleles to identify the genotype of each individual in a sample results in a significant change in the working paradigm of sub-field of quantitative genetics, called variance and covariance analysis, because effects and components of variance and covance may be estimated directly in a sense that will be described in detail in the paper.
Proposal for a Center for the determination of the Causal Transcriptional Consequences of Human
Development Of Molecular Epidemiological Tools For Better Understanding And Control Of Buruli Ulcer
Complete sequences of six Major Histocompatibility Complex haplotypes, including all the major MHC class II structures
Six assembled MHC haplotypes encompass the DR1 and DR4 haplotype structures in addition to the previously completed DR2 and DR3, as well as six distinct classes of the structurally variable C4 region, and can serve as references for the community and provide the basis of a structurally accurate genotyping graph of the complete MHC region.
Once in a Generation: Pascal Mayer and the Birth of a Billion-Dollar Industry
- EconomicsGEN Biotechnology
Synthetic DNA applications in information technology
- Computer ScienceNature communications
An overview of the most prevalent applications of synthetic DNA that could shape the future of information technology and the reasons why the biomolecule can be a valuable alternative for conventional electronic-based media are emphasized.
Systems Biology of Protein Secretion in Human Cells: Multi-omics Analysis and Modeling of the Protein Secretion Process in Human Cells and its Application
A list of genes and pathways that potentially play a crucial role in recombinant protein production and could serve as promising candidates for the targeted cell factory design are identified and identified.
Secuenciación de ADN mediante un algoritmo basado en hidden Markov models para el dispositivo MinION
Los dispositivos MinION son secuenciadores modernos que se caracterizan por su precio y dimensiones bajos respecto a los secuenciadores anteriores. Por estas razones es visto con entusiasmo por…