Genome-wide transcriptome analysis in murine neural retina using high-throughput RNA sequencing.

@article{Gamsiz2012GenomewideTA,
  title={Genome-wide transcriptome analysis in murine neural retina using high-throughput RNA sequencing.},
  author={Ece D. Gamsiz and Qing Ouyang and Michael A. Schmidt and Shailender Nagpal and Eric M. Morrow},
  journal={Genomics},
  year={2012},
  volume={99 1},
  pages={44-51}
}
Genome-wide characterization of the retinal transcriptome is central to understanding development, physiology and disorders of the visual system. Massively parallel, short-read sequencing of mRNA libraries was used to generate an extensive map of the transcriptome of the adult, murine neural retina. RNA-seq data strongly corroborates prior transcriptome studies by microarray and SAGE. However, several novel features of the retinal transcriptome were discovered. For example, retinal disease… CONTINUE READING