Genome-wide transcriptional changes induced by phagocytosis or growth on bacteria in Dictyostelium

@article{Sillo2008GenomewideTC,
  title={Genome-wide transcriptional changes induced by phagocytosis or growth on bacteria in Dictyostelium},
  author={Alessio Sillo and Gareth Bloomfield and Alessandra Balest and Alessandra Balbo and Barbara Pergolizzi and Barbara Peracino and Jason P Skelton and Alasdair C. Ivens and Salvatore Bozzaro},
  journal={BMC Genomics},
  year={2008},
  volume={9},
  pages={291 - 291}
}
Phagocytosis plays a major role in the defense of higher organisms against microbial infection and provides also the basis for antigen processing in the immune response. Cells of the model organism Dictyostelium are professional phagocytes that exploit phagocytosis of bacteria as the preferred way to ingest food, besides killing pathogens. We have investigated Dictyostelium differential gene expression during phagocytosis of non-pathogenic bacteria, using DNA microarrays, in order to identify… CONTINUE READING