Genome-wide transcription responses to synchrotron microbeam radiotherapy.

@article{Sprung2012GenomewideTR,
  title={Genome-wide transcription responses to synchrotron microbeam radiotherapy.},
  author={Carl N. Sprung and Yuqing Yang and Helen B. Forrester and Jason Li and Marina B. Zaitseva and Leonie M. Cann and Tina Restall and Robin L Anderson and Jeffrey C. Crosbie and Peter A. W. Rogers},
  journal={Radiation research},
  year={2012},
  volume={178 4},
  pages={249-59}
}
The majority of cancer patients achieve benefit from radiotherapy. A significant limitation of radiotherapy is its relatively low therapeutic index, defined as the maximum radiation dose that causes acceptable normal tissue damage to the minimum dose required to achieve tumor control. Recently, a new radiotherapy modality using synchrotron-generated X-ray microbeam radiotherapy has been demonstrated in animal models to ablate tumors with concurrent sparing of normal tissue. Very little work has… CONTINUE READING

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Microbeam radiation therapy: Clinical perspectives.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics • 2015
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