Genome-wide significant risk factors for Alzheimer's disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment

@inproceedings{Lacour2017GenomewideSR,
  title={Genome-wide significant risk factors for Alzheimer's disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment},
  author={Andr{\'e} Lacour and Ana Espinosa and Eva Louwersheimer and Stefanie Heilmann and Isabel Hern{\'a}ndez and Steffen Wolfsgruber and Victoria Fern{\'a}ndez and henrik. wagner and Mait{\'e}e Rosende-Roca and Ana Maule{\'o}n and S Moreno-Grau and Liliana Jord{\'a} Vargas and Yolande A. L. Pijnenburg and T. Koene and Octavio Rodr{\'i}guez-G{\'o}mez and Gemma Ortega and Susana Ruiz and Henne Holstege and {\'O}scar Sotolongo-Grau and Johannes Kornhuber and Oliver Peters and Lutz Fr{\"o}lich and Michael H{\"u}ll and Eckart Ruether and Jens Wiltfang and Martin Scherer and Steffi G Riedel-Heller and Montserrat Alegret and Markus M. N{\"o}then and Philip Scheltens and Michaela Wagner and Llu{\'i}s T{\'a}rraga and Frank Jessen and Merç{\'e} Boada and Wolfgang Maier and Wiesje Maria van der Flier and Tim Becker and Aura Mar{\'i}a Ram{\'i}rez and Agust{\'i}n Ru{\'i}z},
  booktitle={Molecular Psychiatry},
  year={2017}
}
Few data are available concerning the role of risk markers for Alzheimer’s disease (AD) in progression to AD dementia among subjects with mild cognitive impairment (MCI). We therefore investigated the role of well-known AD-associated single-nucleotide polymorphism (SNP) in the progression from MCI to AD dementia. Four independent MCI data sets were included in the analysis: (a) the German study on Aging, Cognition and Dementia in primary care patients (n=853); (b) the German Dementia Competence… CONTINUE READING
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