Genome-wide screen of promoter methylation identifies novel markers in melanoma.

@article{Koga2009GenomewideSO,
  title={Genome-wide screen of promoter methylation identifies novel markers in melanoma.},
  author={Yasuo Koga and Mattia Pelizzola and Elaine H. C. Cheng and Michael Krauthammer and Mario Sznol and Stephan Ariyan and Deepak Narayan and Annette M. Molinaro and Ruth Halaban and Sherman Morton Weissman},
  journal={Genome research},
  year={2009},
  volume={19 8},
  pages={1462-70}
}
DNA methylation is an important component of epigenetic modifications, which influences the transcriptional machinery aberrant in many human diseases. In this study we present the first genome-wide integrative analysis of promoter methylation and gene expression for the identification of methylation markers in melanoma. Genome-wide promoter methylation and gene expression of eight early-passage human melanoma cell strains were compared with newborn and adult melanocytes. We used linear mixed… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 85 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 20 references

Similar Papers

Loading similar papers…