Genome-wide screen for cell growth regulators in fission yeast

  title={Genome-wide screen for cell growth regulators in fission yeast},
  author={L. Weston and J. Greenwood and P. Nurse},
  journal={Journal of Cell Science},
  pages={2049 - 2055}
  • L. Weston, J. Greenwood, P. Nurse
  • Published 2017
  • Biology, Medicine
  • Journal of Cell Science
  • ABSTRACT Cellular growth control is important for all living organisms, but experimental investigation into this problem is difficult because of the complex range of growth regulatory mechanisms. Here, we have used the fission yeast Schizosaccharomyces pombe to identify potential master regulators of growth. At the restrictive temperature, the S. pombe pat1ts mei4Δ strain enters the meiotic developmental program, but arrests in meiotic G2 phase as mei4+ is essential for meiotic progression… CONTINUE READING
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