Genome-wide scans for loci under selection in humans

  title={Genome-wide scans for loci under selection in humans},
  author={James Ronald and Joshua M. Akey},
  booktitle={Human Genomics},
Natural selection, which can be defined as the differential contribution of genetic variants to future generations, is the driving force of Darwinian evolution. Identifying regions of the human genome that have been targets of natural selection is an important step in clarifying human evolutionary history and understanding how genetic variation results in phenotypic diversity, it may also facilitate the search for complex disease genes. Technological advances in high-throughput DNA sequencing… CONTINUE READING
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