• Corpus ID: 25804641

Genome-wide scan of 29,141 African Americans finds no evidence of selection since admixture

  title={Genome-wide scan of 29,141 African Americans finds no evidence of selection since admixture},
  author={Gaurav Bhatia and Arti Tandon and Melinda C. Aldrich and Christine B. Ambrosone and Christopher I. Amos and Elisa V. Bandera and Sonja I. Berndt and Leslie Bernstein and William J. Blot and Cathryn H Bock and Neil E. Caporaso and Graham Casey and Sandra L. Deming and W. Ryan Diver and Susan M Gapstur and Elizabeth Gillanders and Curtis C. Harris and Brian E. Henderson and Sue A Ingles and William B. Isaacs and Esther M. John and Rick A. Kittles and Emma Larkin and Lorna H. McNeill and Robert C. Millikan and Adam B. Murphy and Christine Neslund-Dudas and Sarah J Nyante and Michael F Press and Jorge L. Rodriguez-Gil and Benjamin A. Rybicki and Ann G. Schwartz and Lisa B. Signorello and Margaret R. Spitz and Sara S. Strom and Margaret A. Tucker and John K. Wiencke and John S. Witte and Xifeng Wu and Yuko Yamamura and Krista A Zanetti and Wei Zheng and Regina G. Ziegler and Stephen J. Chanock and Christopher A. Haiman and David Reich and Alkes L. Price},
  journal={arXiv: Populations and Evolution},
We scanned through the genomes of 29,141 African Americans, searching for loci where the average proportion of African ancestry deviates significantly from the genome-wide average. We failed to find any genome-wide significant deviations, and conclude that any selection in African Americans since admixture is sufficiently weak that it falls below the threshold of our power to detect it using a large sample size. These results stand in contrast to the findings of a recent study of selection in… 
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