• DOI:10.1017/S0033291714002451
Corpus ID: 4027333

Genome-wide scan demonstrates significant linkage for male sexual orientation.

@article{Sanders2015GenomewideSD,
  title={Genome-wide scan demonstrates significant linkage for male sexual orientation.},
  author={A. Sanders and E. Martin and G. Beecham and S. Guo and K. Dawood and G. Rieger and J. Badner and E. Gershon and R. S. Krishnappa and A. Kolundzija and J. Duan and P. Gejman and J. M. Bailey},
  journal={Psychological medicine},
  year={2015},
  volume={45 7},
  pages={
          1379-88
        }
}

• A. Sanders, E. Martin, +10 authors J. M. Bailey
• Published 2015
• Biology, Medicine
• Psychological medicine

BACKGROUND Findings from family and twin studies support a genetic contribution to the development of sexual orientation in men. However, previous studies have yielded conflicting evidence for linkage to chromosome Xq28. METHOD We conducted a genome-wide linkage scan on 409 independent pairs of homosexual brothers (908 analyzed individuals in 384 families), by far the largest study of its kind to date. RESULTS We identified two regions of linkage: the pericentromeric region on chromosome 8… Expand

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