Genome-wide scan demonstrates significant linkage for male sexual orientation.

@article{Sanders2015GenomewideSD,
  title={Genome-wide scan demonstrates significant linkage for male sexual orientation.},
  author={Alan R. Sanders and Eden R. Martin and Gary W. Beecham and Shengru Guo and Khytam Dawood and Gerulf Rieger and Judith A. Badner and Elliot S. Gershon and Raghunath S Krishnappa and Alana B. Kolundzija and Jubao Duan and Pablo V. Gejman and J Michael Bailey},
  journal={Psychological medicine},
  year={2015},
  volume={45 7},
  pages={
          1379-88
        }
}
BACKGROUND Findings from family and twin studies support a genetic contribution to the development of sexual orientation in men. However, previous studies have yielded conflicting evidence for linkage to chromosome Xq28. METHOD We conducted a genome-wide linkage scan on 409 independent pairs of homosexual brothers (908 analyzed individuals in 384 families), by far the largest study of its kind to date. RESULTS We identified two regions of linkage: the pericentromeric region on chromosome 8… CONTINUE READING

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