Genome-wide regulation of innate immunity by juvenile hormone and 20-hydroxyecdysone in the Bombyx fat body

@inproceedings{Tian2010GenomewideRO,
  title={Genome-wide regulation of innate immunity by juvenile hormone and 20-hydroxyecdysone in the Bombyx fat body},
  author={Ling Tian and Enen Guo and Yupu Diao and Shun Zhou and Qin Peng and Yuanpeng Cao and Erjun Ling and Sheng Li},
  booktitle={BMC Genomics},
  year={2010}
}
Insect innate immunity can be affected by juvenile hormone (JH) and 20-hydroxyecdysone (20E), but how innate immunity is developmentally regulated by these two hormones in insects has not yet been elucidated. In the silkworm, Bombyx mori, JH and 20E levels are high during the final larval molt (4 M) but absent during the feeding stage of 5th instar (5 F), while JH level is low and 20E level is high during the prepupal stage (PP). Fat body produces humoral response molecules and hence is… CONTINUE READING