Genome-wide profiling of target genes for the systemic lupus erythematosus-associated transcription factors IRF5 and STAT4.


BACKGROUND The transcription factors interferon regulatory factor 5 (IRF5) and signal transducer and activator of transcription 4 (STAT4) are encoded by two of the strongest susceptibility genes for systemic lupus erythematosus (SLE). OBJECTIVE To investigate the target genes and functional roles of IRF5 and STAT4 in human peripheral blood mononuclear… (More)
DOI: 10.1136/annrheumdis-2012-201364



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