Genome-wide microarray gene expression, array-CGH analysis, and telomerase activity in advanced ovarian endometriosis: a high degree of differentiation rather than malignant potential.

@article{Zafrakas2008GenomewideMG,
  title={Genome-wide microarray gene expression, array-CGH analysis, and telomerase activity in advanced ovarian endometriosis: a high degree of differentiation rather than malignant potential.},
  author={Menelaos Zafrakas and Basil C. Tarlatzis and Thomas Streichert and Fotios Pournaropoulos and Ute W{\"o}lfle and Serge J. Smeets and Britta Wittek and Grigorios Grimbizis and Ruud H. Brakenhoff and Klaus Pantel and John N. Bontis and Cagatay G{\"u}nes},
  journal={International journal of molecular medicine},
  year={2008},
  volume={21 3},
  pages={335-44}
}
The aim of the present study was to investigate whether endometriosis and cancer share common molecular characteristics. Tissue samples were collected prospectively during diagnostic laparoscopy of patients with primary infertility. Using high-density oligonucleotide microarrays, (Affymetrix Gene Chip HG-U133 Set) the genome-wide gene expression profile of advanced ovarian endometriosis was analyzed compared with matched normal endometrium. Expression of TERT, the gene encoding the telomerase… CONTINUE READING