Genome-wide methylation profiling identifies hypermethylated biomarkers in high-grade cervical intraepithelial neoplasia.

@article{Lendvai2012GenomewideMP,
  title={Genome-wide methylation profiling identifies hypermethylated biomarkers in high-grade cervical intraepithelial neoplasia.},
  author={{\'A}gnes Lendvai and Frank Johannes and Christina Grimm and Jasper J. H. Eijsink and Ren{\'e} Wardenaar and Haukeline H. Volders and Harry G. Klip and Harry Hollema and Ritsert C. Jansen and Ed Schuuring and G Bea A Wisman and Ate G J Van Der Zee},
  journal={Epigenetics},
  year={2012},
  volume={7 11},
  pages={1268-78}
}
Epigenetic modifications, such as aberrant DNA promoter methylation, are frequently observed in cervical cancer. Identification of hypermethylated regions allowing discrimination between normal cervical epithelium and high-grade cervical intraepithelial neoplasia (CIN2/3), or worse, may improve current cervical cancer population-based screening programs. In this study, the DNA methylome of high-grade CIN lesions was studied using genome-wide DNA methylation screening to identify potential… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
21 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…