Genome-wide meta-analysis of cognitive empathy: heritability, and correlates with sex, neuropsychiatric conditions and brain anatomy

@article{Warrier2016GenomewideMO,
  title={Genome-wide meta-analysis of cognitive empathy: heritability, and correlates with sex, neuropsychiatric conditions and brain anatomy},
  author={Varun Warrier and Katrina L. Grasby and Florina Uzefovsky and Roberto Toro and Paula Smith and Bhismadev Chakrabarti and Jyoti Khadake and Eleanor Mawbey-Adamson and Nadia K. Litterman and Jouke- Jan Hottenga and Gitta H. Lubke and Dorret I. Boomsma and Nicholas G. Martin and Peter K. Hatemi and Sarah E. Medland and David A. Hinds and Thomas Bourgeron and Simon Baron-Cohen},
  journal={bioRxiv},
  year={2016}
}
We conducted a genome-wide meta-analysis of cognitive empathy using the ‘Reading the Mind in the Eyes’ Test (Eyes Test) in 88,056 research volunteers of European Ancestry (44,574 females and 43,482 males) from 23andMe Inc., and an additional 1,497 research volunteers of European Ancestry (891 females and 606 males) from the Brisbane Longitudinal Twin Study (BLTS). We confirmed a female advantage on the Eyes Test (Cohen’s d = 0.21, P < 2.2x10−16), and identified a locus in 3p26.1 that is… Expand
Genome-wide meta-analysis of cognitive empathy: heritability, and correlates with sex, neuropsychiatric conditions and cognition
TLDR
A genome-wide meta-analysis of cognitive empathy using the ‘Reading the Mind in the Eyes’ Test (Eyes Test) in 88,056 research volunteers of European Ancestry and an additional 1497 research volunteers from the Brisbane Longitudinal Twin Study identified significant genetic correlation between the Eyes Test and anorexia nervosa, openness, and different measures of educational attainment and cognitive aptitude. Expand
Genome-wide analyses of empathy and systemizing: correlations with psychiatric conditions, psychological traits, and education
TLDR
This study provides the first genetic confirmation of the roles of empathy and systemizing in psychiatric conditions, psychological traits and education. Expand
Genome-wide analyses of self-reported empathy: correlations with autism, schizophrenia, and anorexia nervosa
Abstract Empathy is the ability to recognize and respond to the emotional states of other individuals. It is an important psychological process that facilitates navigating social interactions andExpand
The Eyes as Window to the Mind.
  • S. Baron-Cohen
  • Psychology, Medicine
  • The American journal of psychiatry
  • 2017
TLDR
The authors pit two theories against each other: gaze aversion and gaze indifference, and find that the impairment in autism is very clear, as is thesex difference in typical participants and the absence of any sex difference in autism. Expand

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