Genome-wide mapping of ZNF652 promoter binding sites in breast cancer cells.

  title={Genome-wide mapping of ZNF652 promoter binding sites in breast cancer cells.},
  author={Raman Kumar and Luke A Selth and Ren{\'e}e B. Schulz and Bee Suan Tay and Paul M. Neilsen and David Frederick Callen},
  journal={Journal of cellular biochemistry},
  volume={112 10},
A significant proportion of transcription factors encoded by the human genome are classical C(2) H(2) zinc finger proteins that regulate gene expression by directly interacting with their cognate DNA binding motifs. We previously showed that one such C(2) H(2) zinc finger DNA binding protein, ZNF652 (zinc finger protein 652), specifically and functionally interacts with CBFA2T3 to repress transcription of genes involved in breast oncogenesis. To identify potential targets by which ZNF652 exerts… CONTINUE READING

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