Genome-wide linkage scan of quantitative traits representing symptom dimensions in multiplex schizophrenia families.

@article{Ryu2013GenomewideLS,
  title={Genome-wide linkage scan of quantitative traits representing symptom dimensions in multiplex schizophrenia families.},
  author={Seunghyong Ryu and Hong-Hee Won and Sohee Oh and Jong-Won Kim and Taesung Park and Eun-young Cho and Youngah Cho and Dong Yeon Park and Yu-Sang Lee and Jun Soo Kwon and Kyung Sue Hong},
  journal={Psychiatry research},
  year={2013},
  volume={210 3},
  pages={756-60}
}
Symptom dimensions of schizophrenia are likely to be the intermediate phenotypes under the control of disease-susceptibility genes, or separate traits related to disease-modifier genes. This study aimed to identify chromosomal loci linked to symptom dimensions of schizophrenia through genome-wide quantitative trait locus (QTL) linkage analysis. The study subjects consisted of 56 families with 183 members including 123 affected individuals. Symptom evaluations were performed on lifetime basis… CONTINUE READING
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