Genome-wide linkage disequilibrium mapping of late-onset Alzheimer's disease in Finland.


BACKGROUND AD is a complex neurodegenerative disorder comprising several disease-associated chromosome loci. To find novel susceptibility genes for late-onset AD, a population-based genome-wide search using linkage disequilibrium (LD) mapping approach has been performed. METHOD Forty-seven patients with late-onset AD and 51 age-matched control subjects… (More)


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