Genome-wide linkage analysis for smoking-related regions, with replication in two ethnically diverse populations.

@article{Pomerleau2007GenomewideLA,
  title={Genome-wide linkage analysis for smoking-related regions, with replication in two ethnically diverse populations.},
  author={Ovide F. Pomerleau and Cynthia S. Pomerleau and Jian Chu and Sharon L. R. Kardia},
  journal={Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco},
  year={2007},
  volume={9 9},
  pages={955-8}
}
As part of the Genetic Epidemiology Network of Arteriopathy, hypertensive sibships were collected and smoking behavior recorded. Using an affected sibpair design and genome-wide microsatellite data markers ( approximately 10 cM coverage), we identified 214 non-Hispanic White sibships (502 sibpairs) from Rochester, Minnesota (M (age) [SD] = 55.68 years [10.56]) and 206 Black sibships (376 sibpairs) from Jackson, Mississippi (M (age) = 57.97 [8.94]), who had smoked for at least 3 years, and… CONTINUE READING