Genome-wide immunity studies in the rabbit: transcriptome variations in peripheral blood mononuclear cells after in vitro stimulation by LPS or PMA-Ionomycin

@inproceedings{Jacquier2015GenomewideIS,
  title={Genome-wide immunity studies in the rabbit: transcriptome variations in peripheral blood mononuclear cells after in vitro stimulation by LPS or PMA-Ionomycin},
  author={Vincent Jacquier and Jordi Estell{\'e} and Barbara Schmaltz-Panneau and J{\'e}r{\^o}me Lecardonnel and Marco Moroldo and Ga{\"e}tan Lemonnier and Jason Turner-Maier and V{\'e}ronique Duranthon and Isabelle P Oswald and Thierry Gidenne and Claire Rogel-Gaillard},
  booktitle={BMC Genomics},
  year={2015}
}
Our purpose was to obtain genome-wide expression data for the rabbit species on the responses of peripheral blood mononuclear cells (PBMCs) after in vitro stimulation by lipopolysaccharide (LPS) or phorbol myristate acetate (PMA) and ionomycin. This transcriptome profiling was carried out using microarrays enriched with immunity-related genes, and annotated with the most recent data available for the rabbit genome. The LPS affected 15 to 20 times fewer genes than PMA-Ionomycin after both 4… CONTINUE READING
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