Genome-wide identification of genes required for growth of Saccharomyces cerevisiae under ethanol stress.

@article{Voorst2006GenomewideIO,
  title={Genome-wide identification of genes required for growth of Saccharomyces cerevisiae under ethanol stress.},
  author={Frank van Voorst and Jens Houghton-Larsen and Lars J\onson and Morten C. Kielland-Brandt and Anders Brandt},
  journal={Yeast},
  year={2006},
  volume={23 5},
  pages={
          351-9
        }
}
The Saccharomyces cerevisiae deletion collection was screened for impaired growth on glucose-based complex medium containing 6% ethanol. Forty-six mutants were found. Genes encoding proteins involved in vacuolar function, the cell integrity pathway, mitochondrial function, subunits of the co-chaperone complex GimC and components of the SAGA transcription factor complex were in this way found to be important for the growth of wild-type Saccharomyces yeast in the presence of ethanol. Several… CONTINUE READING