Genome-wide identification of copy number variations between two chicken lines that differ in genetic resistance to Marek’s disease

@inproceedings{Yan2015GenomewideIO,
  title={Genome-wide identification of copy number variations between two chicken lines that differ in genetic resistance to Marek’s disease},
  author={Yiyuan Yan and Ning Yang and Hans H. Cheng and Jiuzhou Song and Lujiang Qu},
  booktitle={BMC Genomics},
  year={2015}
}
Copy number variation (CNV) is a major source of genome polymorphism that directly contributes to phenotypic variation such as resistance to infectious diseases. Lines 63 and 72 are two highly inbred experimental chicken lines that differ greatly in susceptibility to Marek’s disease (MD), and have been used extensively in efforts to identify the genetic and molecular basis for genetic resistance to MD. Using next generation sequencing, we present a genome-wide assessment of CNVs that are… CONTINUE READING

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