Genome-wide gene-based analysis suggests an association between Neuroligin 1 ( NLGN 1 ) and post-traumatic stress disorder

@inproceedings{Kilaru2016GenomewideGA,
  title={Genome-wide gene-based analysis suggests an association between Neuroligin 1 ( NLGN 1 ) and post-traumatic stress disorder},
  author={Varun Kilaru and S. Iyer and LM Almli and JS Stevens and Andrea Lori and Tanja Jovanovic and TD Ely and Brent Bradley and EB Binder and Nadia Koen and D. J. Stein and KN Conneely and AP Wingo and A Smith and KJ Ressler},
  year={2016}
}
Post-traumatic stress disorder (PTSD) develops in only some people following trauma exposure, but the mechanisms differentially explaining risk versus resilience remain largely unknown. PTSD is heritable but candidate gene studies and genome-wide association studies (GWAS) have identified only a modest number of genes that reliably contribute to PTSD. New gene-based methods may help identify additional genes that increase risk for PTSD development or severity. We applied gene-based testing to… CONTINUE READING
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