Genome-wide functional analysis reveals that infection-associated fungal autophagy is necessary for rice blast disease.

@article{Kershaw2009GenomewideFA,
  title={Genome-wide functional analysis reveals that infection-associated fungal autophagy is necessary for rice blast disease.},
  author={Michael J. Kershaw and Nicholas J. Talbot},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2009},
  volume={106 37},
  pages={15967-72}
}
To cause rice blast disease, the fungus Magnaporthe oryzae elaborates specialized infection structures called appressoria, which use enormous turgor to rupture the tough outer cuticle of a rice leaf. Here, we report the generation of a set of 22 isogenic M. oryzae mutants each differing by a single component of the predicted autophagic machinery of the fungus. Analysis of this set of targeted deletion mutants demonstrated that loss of any of the 16 genes necessary for nonselective… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 69 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 50 references

Genetic analysis of melanin - deficient , nonpathogenic mutants of . Magnaporthe grisea

  • E Itakura, C Kishi, K Inoue, N Mizushima
  • Molec Plant Microbe Interact
  • 2008

Guidelines for the use and interpretations of assays for monitoring autophagy in higher eukaryotes

  • DJ Klionsky
  • Autophagy
  • 2008

Similar Papers

Loading similar papers…