Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis.

@article{Sweeney2016GenomewideEF,
  title={Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis.},
  author={Timothy E. Sweeney and Lindsay Braviak and Cristina M. Tato and Purvesh Khatri},
  journal={The Lancet. Respiratory medicine},
  year={2016},
  volume={4 3},
  pages={213-24}
}
BACKGROUND Active pulmonary tuberculosis is difficult to diagnose and treatment response is difficult to effectively monitor. A WHO consensus statement has called for new non-sputum diagnostics. The aim of this study was to use an integrated multicohort analysis of samples from publically available datasets to derive a diagnostic gene set in the peripheral blood of patients with active tuberculosis. METHODS We searched two public gene expression microarray repositories and retained datasets… CONTINUE READING