Genome-wide evolutionary analysis of eukaryotic DNA methylation.

@article{Zemach2010GenomewideEA,
  title={Genome-wide evolutionary analysis of eukaryotic DNA methylation.},
  author={Assaf Zemach and Ivy E. McDaniel and Pedro Silva and Daniel Zilberman},
  journal={Science},
  year={2010},
  volume={328 5980},
  pages={916-9}
}
Eukaryotic cytosine methylation represses transcription but also occurs in the bodies of active genes, and the extent of methylation biology conservation is unclear. We quantified DNA methylation in 17 eukaryotic genomes and found that gene body methylation is conserved between plants and animals, whereas selective methylation of transposons is not. We show that methylation of plant transposons in the CHG context extends to green algae and that exclusion of histone H2A.Z from methylated DNA is… CONTINUE READING
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