Genome-wide comparative analysis reveals human-mouse regulatory landscape and evolution

@inproceedings{Denas2015GenomewideCA,
  title={Genome-wide comparative analysis reveals human-mouse regulatory landscape and evolution},
  author={Olgert Denas and Richard S. Sandstrom and Yong Cheng and Kathryn Beal and Javier M. Herrero and Ross C. Hardison and James Taylor},
  booktitle={BMC Genomics},
  year={2015}
}
Because species-specific gene expression is driven by species-specific regulation, understanding the relationship between sequence and function of the regulatory regions in different species will help elucidate how differences among species arise. Despite active experimental and computational research, relationships among sequence, conservation, and… CONTINUE READING

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