Genome-wide biological response fingerprinting (BioReF) of the Chinese botanical formulation ISF-1 enables the selection of multiple marker genes as a potential metric for quality control.

@article{Rong2007GenomewideBR,
  title={Genome-wide biological response fingerprinting (BioReF) of the Chinese botanical formulation ISF-1 enables the selection of multiple marker genes as a potential metric for quality control.},
  author={Jianhui Rong and Robert Tilton and Jiangang Shen and Kwan-Ming Ng and Chang Liu and Paul Kwong-hang Tam and Allan Sik-Yin Lau and Yung-chi Cheng},
  journal={Journal of ethnopharmacology},
  year={2007},
  volume={113 1},
  pages={35-44}
}
Quality control plays a critical role in the process of translating the traditional/alternative medicines into modern evidence-based therapies. High performance liquid chromatography (HPLC) is widely applied to assess the chemical composition of botanical drug products. The chromatographic fingerprints or chemical profiles are currently used as the de facto quality control metric. As a complement to chemical profiles, a biological quality control assessment offers distinct advantages. This… CONTINUE READING