Genome-wide association study of prostate cancer identifies a second risk locus at 8q24

@article{Yeager2007GenomewideAS,
  title={Genome-wide association study of prostate cancer identifies a second risk locus at 8q24},
  author={M. Yeager and N. Orr and R. Hayes and K. Jacobs and P. Kraft and S. Wacholder and Mark J Minichiello and P. Fearnhead and K. Yu and N. Chatterjee and Z. Wang and R. Welch and B. Staats and E. Calle and H. Feigelson and M. Thun and C. Rodr{\'i}guez and D. Albanes and J. Virtamo and S. Weinstein and F. Schumacher and E. Giovannucci and W. Willett and G. Cancel-Tassin and O. Cussenot and A. Val{\'e}ri and G. Andriole and E. Gelmann and M. Tucker and D. Gerhard and J. Fraumeni and R. Hoover and D. Hunter and S. Chanock and G. Thomas},
  journal={Nature Genetics},
  year={2007},
  volume={39},
  pages={645-649}
}
Recently, common variants on human chromosome 8q24 were found to be associated with prostate cancer risk. While conducting a genome-wide association study in the Cancer Genetic Markers of Susceptibility project with 550,000 SNPs in a nested case-control study (1,172 cases and 1,157 controls of European origin), we identified a new association at 8q24 with an independent effect on prostate cancer susceptibility. The most significant signal is 70 kb centromeric to the previously reported SNP… Expand

Paper Mentions

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