Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid

@article{Luykx2014GenomewideAS,
  title={Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid},
  author={J. Luykx and S. Bakker and E. Lentjes and M. Neeleman and E. Strengman and L. Mentink and J. Deyoung and S. D. Jong and J. Sul and E. Eskin and K. V. Eijk and J. Setten and J. Buizer-Voskamp and R. Cantor and A. Lu and M. Amerongen and E. P. Dongen and P. Keijzers and T. Kappen and P. Borgdorff and P. Bruins and E. Derks and R. Kahn and R. Ophoff},
  journal={Molecular Psychiatry},
  year={2014},
  volume={19},
  pages={228-234}
}
Studying genetic determinants of intermediate phenotypes is a powerful tool to increase our understanding of genotype–phenotype correlations. Metabolic traits pertinent to the central nervous system (CNS) constitute a potentially informative target for genetic studies of intermediate phenotypes as their genetic underpinnings may elucidate etiological mechanisms. We therefore conducted a genome-wide association study (GWAS) of monoamine metabolite (MM) levels in cerebrospinal fluid (CSF) of 414… Expand
47 Citations
Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels
  • 1
  • PDF
Genome-wide association study of NMDA receptor coagonists in human cerebrospinal fluid and plasma
  • 9
  • PDF
Whole blood transcriptome analysis in bipolar disorder reveals strong lithium effect
  • 2
  • PDF
De novo deleterious variants that may alter the dopaminergic reward pathway are associated with anorexia nervosa
  • 3
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 69 REFERENCES
A genome-wide association study of metabolic traits in human urine
  • 210
Genome-wide association study identifies five new schizophrenia loci
  • 1,587
  • PDF
TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies
  • 133
  • PDF
A Common Variant in ERBB4 Regulates GABA Concentrations in Human Cerebrospinal Fluid
  • 18
  • PDF
...
1
2
3
4
5
...