Genome-wide association study of antipsychotic induced QTc interval prolongation


QT prolongation is associated with increased risk of cardiac arrhythmias. Identifying the genetic variants that mediate antipsychotic-induced prolongation may help to minimize this risk, which might prevent the removal of efficacious drugs from the market. We performed candidate gene analysis and five drug-specific genome-wide association studies (GWASs… (More)
DOI: 10.1038/tpj.2010.76


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