Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.

@article{Chimusa2014GenomewideAS,
  title={Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.},
  author={Emile R. Chimusa and Noah A. Zaitlen and Michelle Daya and Marlo M{\"o}ller and Paul D van Helden and Nicola J. Mulder and Alkes L. Price and Eileen G Hoal},
  journal={Human molecular genetics},
  year={2014},
  volume={23 3},
  pages={796-809}
}
The worldwide burden of tuberculosis (TB) remains an enormous problem, and is particularly severe in the admixed South African Coloured (SAC) population residing in the Western Cape. Despite evidence from twin studies suggesting a strong genetic component to TB resistance, only a few loci have been identified to date. In this work, we conduct a genome-wide association study (GWAS), meta-analysis and trans-ethnic fine mapping to attempt the replication of previously identified TB susceptibility… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 35 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 56 references

African TB Genetics Consortium, The Wellcome Trust Case Control

  • T. Thye, F. O. Vannberg, +24 authors A. Ziegler
  • Nat. Genet.,
  • 2010
Highly Influential
2 Excerpts

Similar Papers

Loading similar papers…