Genome-wide association study in German patients with attention deficit/hyperactivity disorder.

  title={Genome-wide association study in German patients with attention deficit/hyperactivity disorder.},
  author={Anke Hinney and Andr{\'e} Scherag and Ivonne Jarick and {\"O}zg{\"u}r Albayrak and Carolin P{\"u}tter and Sonali Pechlivanis and Maria R Dauvermann and Sebastian Beck and Heike Weber and Susann Scherag and Trang T. Nguyen and A. Volckmar and Nadja Knoll and Stephen V Faraone and Benjamin M. Neale and Barbara Franke and Sven Cichon and Per Hoffmann and Markus M. N{\"o}then and Stefan Schreiber and Karl-Heinz J{\"o}ckel and H. M. Wichmann and Christine Freitag and Thomas Lempp and Jobst Meyer and Susanne Gilsbach and Beate Herpertz-Dahlmann and Judith Sinzig and Gerd Lehmkuhl and Tobias Renner and Andreas Warnke and Marcel Romanos and Klaus-Peter Lesch and Andreas Reif and Benno Graf Schimmelmann and Johannes Hebebrand},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  volume={156B 8},
The heritability of attention deficit hyperactivity disorder (ADHD) is approximately 0.8. Despite several larger scale attempts, genome-wide association studies (GWAS) have not led to the identification of significant results. We performed a GWAS based on 495 German young patients with ADHD (according to DSM-IV criteria; Human660W-Quadv1; Illumina, San Diego, CA) and on 1,300 population-based adult controls (HumanHap550v3; Illumina). Some genes neighboring the single nucleotide polymorphisms… CONTINUE READING
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