Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms

@article{Wang2011GenomewideAS,
  title={Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms},
  author={Ke-Sheng Wang and Xuefeng Liu and Qunyuan Zhang and Long-Yang Wu and Min Zeng},
  journal={Journal of Neural Transmission},
  year={2011},
  volume={119},
  pages={425-433}
}
Several genome-wide association (GWA) studies of alcohol dependence (AD) and alcohol-related phenotypes have been conducted; however, little is known about genetic variants influencing alcohol withdrawal symptoms (AWS). We conducted the first GWA study of AWS using 461 cases of AD with AWS and 408 controls in Caucasian population in the Collaborative Study on the Genetics of Alcoholism (COGA) sample. Logistic regression analysis of AWS as a binary trait, adjusted for age and sex, was performed… CONTINUE READING
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