Genome-wide association studies in mice

@article{Flint2012GenomewideAS,
  title={Genome-wide association studies in mice},
  author={Jonathan Flint and Eleazar Eskin},
  journal={Nature Reviews Genetics},
  year={2012},
  volume={13},
  pages={807-817}
}
Genome-wide association studies (GWASs) have transformed the field of human genetics and have led to the discovery of hundreds of genes that are implicated in human disease. The technological advances that drove this revolution are now poised to transform genetic studies in model organisms, including mice. However, the design of GWASs in mouse strains is fundamentally different from the design of human GWASs, creating new challenges and opportunities. This Review gives an overview of the novel… CONTINUE READING

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