Genome-wide association studies for common diseases and complex traits

Abstract

Genetic factors strongly affect susceptibility to common diseases and also influence disease-related quantitative traits. Identifying the relevant genes has been difficult, in part because each causal gene only makes a small contribution to overall heritability. Genetic association studies offer a potentially powerful approach for mapping causal genes with… (More)
DOI: 10.1038/nrg1521

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@article{Hirschhorn2005GenomewideAS, title={Genome-wide association studies for common diseases and complex traits}, author={Joel Hirschhorn and Mark J. Daly}, journal={Nature Reviews Genetics}, year={2005}, volume={6}, pages={95-108} }