Genome-wide analysis of three-way interplay among gene expression, cancer cell invasion and anti-cancer compound sensitivity

@inproceedings{Hsu2013GenomewideAO,
  title={Genome-wide analysis of three-way interplay among gene expression, cancer cell invasion and anti-cancer compound sensitivity},
  author={Yi-Chiung Hsu and Hsuan-Yu Chen and Shinsheng Yuan and Sung-Liang Yu and Chia-Hung Lin and Guani Wu and Pan Yang and K C Li},
  booktitle={BMC medicine},
  year={2013}
}
BACKGROUND Chemosensitivity and tumor metastasis are two primary issues in cancer management. Cancer cells often exhibit a wide range of sensitivity to anti-cancer compounds. To gain insight on the genetic mechanism of drug sensitivity, one powerful approach is to employ the panel of 60 human cancer cell lines developed by the National Cancer Institute (NCI… CONTINUE READING