Genome-wide analysis of phenobarbital-inducible genes in Drosophila melanogaster.

  title={Genome-wide analysis of phenobarbital-inducible genes in Drosophila melanogaster.},
  author={W. Sun and Venu M. Margam and Ling Ling Sun and Grzegorz A. Buczkowski and Gary W. Bennett and Brandi J. Schemerhorn and William M. Muir and Barry R. Pittendrigh},
  journal={Insect molecular biology},
  volume={15 4},
An oligoarray analysis was conducted to determine the differential expression of genes due to phenobarbital exposure in Drosophila melanogaster (w(1118) strain) third instar larvae. Seventeen genes were observed to be induced with increased expression by a statistical analysis of microarrays approach with a q < or = 0.05. At q < or = 0.12, four more genes (Cyp12d1, DmGstd4, and two genes with unknown function) were found to be up-regulated, and 11 genes with unknown function were found to be… CONTINUE READING

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