Genome-wide analysis of longevity in nutrient-deprived Saccharomyces cerevisiae reveals importance of recycling in maintaining cell viability.

@article{Davey2012GenomewideAO,
  title={Genome-wide analysis of longevity in nutrient-deprived Saccharomyces cerevisiae reveals importance of recycling in maintaining cell viability.},
  author={Hazel Marie Davey and Emma J. M. Cross and Christopher Lyndon Davey and Konstantinos Gkargkas and Daniela Delneri and David C. Hoyle and Stephen G. Oliver and Douglas B. Kell and Gareth W. Griffith},
  journal={Environmental microbiology},
  year={2012},
  volume={14 5},
  pages={1249-60}
}
Although typically cosseted in the laboratory with constant temperatures and plentiful nutrients, microbes are frequently exposed to much more stressful conditions in their natural environments where survival and competitive fitness depend upon both growth rate when conditions are favourable and on persistence in a viable and recoverable state when they are not. In order to determine the role of genetic heterogeneity in environmental fitness we present a novel approach that combines the power… CONTINUE READING
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