Genome-wide analysis of core promoter elements from conserved human and mouse orthologous pairs

@article{Jin2005GenomewideAO,
  title={Genome-wide analysis of core promoter elements from conserved human and mouse orthologous pairs},
  author={Victor X. Jin and Gregory A. Singer and Francisco J. Agosto-Perez and Sandya Liyanarachchi and Ramana V. Davuluri},
  journal={BMC Bioinformatics},
  year={2005},
  volume={7},
  pages={114 - 114}
}
The canonical core promoter elements consist of the TATA box, initiator (Inr), downstream core promoter element (DPE), TFIIB recognition element (BRE) and the newly-discovered motif 10 element (MTE). The motifs for these core promoter elements are highly degenerate, which tends to lead to a high false discovery rate when attempting to detect them in promoter sequences. In this study, we have performed the first analysis of these core promoter elements in orthologous mouse and human promoters… CONTINUE READING

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