Genome-wide analysis of DNA methylation and the gene expression change in lung cancer.

@article{Kwon2012GenomewideAO,
  title={Genome-wide analysis of DNA methylation and the gene expression change in lung cancer.},
  author={Yong-Jae Kwon and Seog Joo Lee and Jae Soo Koh and Sung Han Kim and Hye Won Lee and Moon Chul Kang and Jae Bum Bae and Young-Joon Kim and Jong Ho Park},
  journal={Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer},
  year={2012},
  volume={7 1},
  pages={20-33}
}
INTRODUCTION The recent DNA methylation studies on cancers have revealed the necessity of profiling an entire human genome and not to restrict the profiling to specific regions of the human genome. It has been suggested that genome-wide DNA methylation analysis enables us to identify the genes that are regulated by DNA methylation in carcinogenesis. METHODS So, we performed whole-genome DNA methylation analysis for human lung squamous cell carcinoma (SCC), which is strongly related with… CONTINUE READING