Genome-wide analysis and expression profiling of the small heat shock proteins in zebrafish.

@article{Elicker2007GenomewideAA,
  title={Genome-wide analysis and expression profiling of the small heat shock proteins in zebrafish.},
  author={Kimberly S Elicker and Lara D. Hutson},
  journal={Gene},
  year={2007},
  volume={403 1-2},
  pages={60-9}
}
Small Heat Shock Proteins (sHSPs) have important roles in preventing disease and promoting resistance to environmental stressors. Mutations in any one of a number of sHSPs, including HSP27 (HSPB1), HSP22 (HSPB8), alphaA-crystallin (HSPB4), or alphaB-crystallin (HSPB5) can result in neuronal degeneration, myopathy, and/or cataract in humans. Ten sHSPs are known in humans, and thirteen have been identified in teleost fish. Here we report the identification of thirteen zebrafish sHSPs. Using a… CONTINUE READING
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