Genome-wide analyses reveal a role for peptide hormones in planarian germline development.

@article{Collins2010GenomewideAR,
  title={Genome-wide analyses reveal a role for peptide hormones in planarian germline development.},
  author={James J Collins and Xiaowen Hou and Elena V Romanova and Bramwell G. Lambrus and Claire M. Miller and Amir Saberi and Jonathan V. Sweedler and Phillip A Newmark},
  journal={PLoS biology},
  year={2010},
  volume={8 10},
  pages={e1000509}
}
Bioactive peptides (i.e., neuropeptides or peptide hormones) represent the largest class of cell-cell signaling molecules in metazoans and are potent regulators of neural and physiological function. In vertebrates, peptide hormones play an integral role in endocrine signaling between the brain and the gonads that controls reproductive development, yet few of these molecules have been shown to influence reproductive development in invertebrates. Here, we define a role for peptide hormones in… CONTINUE READING

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