Genome wide SNP array identified multiple mechanisms of genetic changes in Waldenstrom macroglobulinemia.

Abstract

SNP array (SNPa) was developed to detect copy number alteration (CNA) and loss of heterozygosity (LOH) without copy number changes, CN-LOH. We aimed to identify novel genomic aberrations using SNPa in 31 WM with paired samples. Methylation status and mutation were analyzed on target genes. A total of 61 genetic aberrations were observed, 58 CNA (33 gains… (More)
DOI: 10.1002/ajh.23545

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