Genome-wide Pathway Analysis Using Gene Expression Data of Colonic Mucosa in Patients with Inflammatory Bowel Disease

@inproceedings{Palmieri2015GenomewidePA,
  title={Genome-wide Pathway Analysis Using Gene Expression Data of Colonic Mucosa in Patients with Inflammatory Bowel Disease},
  author={Orazio Palmieri and Teresa Maria Creanza and Fabrizio Bossa and Orazio Palumbo and Rosalia Maglietta and Nicola Ancona and Giuseppe Corritore and Tiziana Pia Latiano and Giuseppina Martino and Giuseppe Biscaglia and Daniela Scimeca and Michele Pio De Petris and Massimo Carella and Vito Annese and Angelo Andriulli and Anna Latiano},
  booktitle={Inflammatory bowel diseases},
  year={2015}
}
BACKGROUND Ulcerative colitis (UC) and Crohn's disease (CD) share some pathogenetic features. To provide new steps on the role of altered gene expression, and the involvement of gene networks, in the pathogenesis of these diseases, we performed a genome-wide analysis in 15 patients with CD and 14 patients with UC by comparing the RNA from inflamed and noninflamed colonic mucosa. METHODS Two hundred ninety-eight differentially expressed genes in CD and 520 genes in UC were identified. By… CONTINUE READING
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