Genome-wide DNA methylation profiling of peripheral blood mononuclear cells in irritable bowel syndrome.

Abstract

BACKGROUND Irritable bowel syndrome (IBS) is a stress-sensitive disorder. Environmental factors including stress can trigger epigenetic changes, which have not been well-studied in IBS. We performed a pilot study investigating genome-wide DNA methylation of IBS patients and healthy controls (HCs) to identify potential epigenetic markers and associated… (More)
DOI: 10.1111/nmo.12741

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