Genome-wide DNA methylation analysis reveals hypomethylation in the low-CpG promoter regions in lymphoblastoid cell lines

@inproceedings{Taniguchi2017GenomewideDM,
  title={Genome-wide DNA methylation analysis reveals hypomethylation in the low-CpG promoter regions in lymphoblastoid cell lines},
  author={Itsuki Taniguchi and Chihiro Iwaya and Keizo Ohnaka and Hiroki Shibata and Ken Yamamoto},
  booktitle={Human Genomics},
  year={2017}
}
Epidemiological studies of DNA methylation profiles may uncover the molecular mechanisms through which genetic and environmental factors contribute to the risk of multifactorial diseases. There are two types of commonly used DNA bioresources, peripheral blood cells (PBCs) and EBV-transformed lymphoblastoid cell lines (LCLs), which are available for genetic epidemiological studies. Therefore, to extend our knowledge of the difference in DNA methylation status between LCLs and PBCs is important… CONTINUE READING
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