Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1) provides insights into genome evolution

  title={Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1) provides insights into genome evolution},
  author={Fuguang Li and Guangyi Fan and Cairui Lu and Guanghui Xiao and Changsong Zou and Russell J. Kohel and Zhiying Ma and Haihong Shang and Xiongfeng Ma and Jian-Yong Wu and Xinming Liang and Gai Huang and Richard G. Percy and Kun Liu and Wei-hua Yang and Wenbin Chen and Xiongming Du and Chengcheng Shi and Youlu Yuan and Wuwei Ye and Xin Liu and Xueyan Zhang and Weiqing Liu and Hengling Wei and Shoujun Wei and Guodong Huang and Xianlong Zhang and Shui Jin Zhu and He Zhang and Fengming Sun and Xingfen Wang and Jie Liang and Jiahao Wang and Qiang He and Leihuan Huang and Jun Wang and Jinjie Cui and Guoli Song and Kunbo Wang and Xun Xu and John Z. Yu and Yuxian Zhu and Shuxun Yu},
  journal={Nature Biotechnology},
Gossypium hirsutum has proven difficult to sequence owing to its complex allotetraploid (AtDt) genome. Here we produce a draft genome using 181-fold paired-end sequences assisted by fivefold BAC-to-BAC sequences and a high-resolution genetic map. In our assembly 88.5% of the 2,173-Mb scaffolds, which cover 89.6%∼96.7% of the AtDt genome, are anchored and oriented to 26 pseudochromosomes. Comparison of this G. hirsutum AtDt genome with the already sequenced diploid Gossypium arboreum (AA) and… CONTINUE READING
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